ACR Highlights… ACR Convergence Highlights 2023 – Basic Research I: Genetics, cartilage/synovium, osteoimmunology, animal models 9 Dec 20239 Dec 2023 Author: Rami Bechara Hou et al. (0733) utilised CRISPR/Cas9 technology to identify cell type-specific functional variants that regulate the Type I interferon pathway in lupus. Notably, they discovered the negative regulatory effect…
ACR Highlights… ACR Convergence Highlights 2023 – Basic Research II: Immunity, Immunology 9 Dec 20239 Dec 2023 Author: Latika Gupta Ghossan et al. (0732) established that while B cell depletion is associated with a better response to RTX at the start of treatment, the persistence of complete B cell depletion is not…
ACR Highlights… ACR Convergence Highlights 2023 – Rheumatoid Arthritis: Clinical (therapeutic) 9 Dec 20239 Dec 2023 Author: Victoria Konzett Cope et al. (0835) investigated the efficacy of T-cell co-stimulation with Abatacept on prevention of disease onset in an autoantibody-positive population with arthralgia at risk of developing RA,…
ACR Highlights… ACR Convergence Highlights 2023 – Spondyloarthritis I: Clinical (non-therapeutic) 9 Dec 20239 Dec 2023 Author: Olivier Fakih Michel et al. (2222) compared patients with a SpA + IBD codiagnosis versus those with only one diagnosis in a retrospective monocentric study. 62 patients with a…
ACR Highlights… ACR Convergence Highlights 2023 – Spondyloarthritis II: Clinical (therapeutic) 9 Dec 20239 Dec 2023 Author: Bayram Farisogullari Kivitz et al. (0776) investigated the long-term efficacy, safety, and tolerability of intravenous (IV) secukinumab (SEC) in patients with active PsA through 52 weeks in a randomised,…
ACR Highlights… ACR Convergence Highlights 2023 – SLE and APS 9 Dec 20239 Dec 2023 Author: Anastasia Madenidou Schett et al. (0607) followed up 8 SLE patients who received treatment with CD19 CAR T cell therapy. Five patients had a follow-up of more than one year…
ACR Highlights… ACR Convergence Highlights 2023 – Metabolic & Crystal arthropathies 9 Dec 20239 Dec 2023 Author: Dálifer Freites Núñez Tedeschi et al. (0234) performed a secondary analysis using data from the Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (CARES) trial. Among 6183 participants in this analysis,…
ACR Highlights… ACR Convergence Highlights 2023 – Other Connective Tissues Diseases and Vasculitis 9 Dec 20239 Dec 2023 Author: Lisa Christ Bergmann et al. (2598) observed stabilisation of disease activity in 3 systemic sclerosis (Ssc) patients treated with CD19 CAR T-cells at 6 months follow-up. Taubmann et al.…
ACR Highlights… ACR Convergence Highlights 2023 – Rare & Autoinflammatory diseases 9 Dec 20239 Dec 2023 Author: Dálifer Freites Núñez Brown et al. (0280) characterized the largest cohort of patients suffering from Susac Syndrome, a rare autoimmune condition causing microvascular occlusions in the brain, retina and inner ear leading to…
ACR Highlights… ACR Convergence Highlights 2023 – Paediatric Rheumatology 9 Dec 20239 Dec 2023 Author: Jessica Perfetto Matt et al. (0363) assessed clinical, inflammatory, and pulmonary outcomes of post-allogenic hematopoietic stem cell transplant (HSCT) in an international cohort of children with refractory systemic JIA…