Sónia Melo Gomes
Sónia is a Clinical Research Fellow who recently finished her PhD in genetics of Autoinflammation at the UCL GOSH Institute of Child Health in London, UK. She is also a member of the executive committee of EMERGE, with responsibilities in the organization of the Young Investigators Meeting as well as being the lead of the Global Affairs and Country Liaison Subcommittee.
| Poster 0830 | Sunday, 12.11.23 16.15 Pediatric Rheumatology – Clinical I: JIA Author: Eloseily, E (USA) Title: THE UPREGULATION OF MAP KINASE GENES IS ASSOCIATED WITH POOR TREATMENT RESPONSE TO TOFATICINIB IN POLYARTICULAR COURSE JUVENILE IDIOPATHIC ARTHRITIS  In this study the increased expression of MAP Kinase genes was associated with poor treatment response to Tofacitinib in polyarticular JIA. |
| Poster 0831 | Sunday, 12.11.23 16.15 Pediatric Rheumatology – Clinical I: JIA Author: Ringold, S (USA) Title: TWO- AND THREE-YEAR OUTCOMES OF FROM THE CHILDHOOD ARTHRITIS AND RHEUMATOLOGY RESEARCH ALLIANCE START TIME OPTIMIZATION OF BIOLOGIC THERAPY IN POLYARTICULAR JIA (STOP JIA) STUDY This study showed improved effectiveness of early combination therapy for most outcomes, including limitation of disease burden. |
| Poster 1228 | Monday, 13.11.23 09.00 Pediatric Rheumatology – Clinical Poster II: Connective Tissue Disease Author: Kone Paut, I (France) Title: VALIDATION OF THE PEDIATRIC BEHCET’S DISEASE CLASSIFICATION CRITERIA (PEDBD): AN INTERNATIONAL CONCENSUS APPROACH This international consensus study for validating the PEDBD criteria showed higher specific but lower sensitivity than ICBD criteria. |
| Oral 1247 | Monday, 13.11.23 09.00 Pediatric Rheumatology – Clinical Poster II: Connective Tissue Disease Author: Brunner, H (USA) Title: PHARMACOKINETIC, PHARMACODYNAMIC AND SAFETY PROFILE OF SC BELIMUMAB IN PEDIATRIC PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS: ANALYSIS OF DATA FROM A MULTICENTER OPEN LABEL TRIAL In this open-label trial sc Belimumab exposure in pediatric patients was similar to adult data, with no new safety concerns. |
| Oral 1623 | Monday 13.11.23 14.30 Pediatric Rheumatology – Clinical II: Connective Tissue Disease Author: Foldvari, I (Germany) Title: DIFFUSE JUVENILE SYSTEMIC SCLEROSIS PATIENTS SHOW DISTINCT ORGAN INVOLVEMENT, ANTIBODY PATTERN AND HAVE MORE SEVERE DISEASE IN THE LARGEST jSSc COHORT OF THE WORLD. RESULTS FROM THE JUVENILE SCLERODERMA INCEPTION COHORT This large cohort showed that djSSc had more severe outcomes, but cardiac involvement was more frequent in ljSSc, with no statistical difference regarding ILD and PHT between both groups. |
| Oral 1882 | Tuesday 14.11.23 11:00 AM Pediatric Rheumatology – Basic Science Author: Canna, S (US) Title: CHRONIC EXCESS IL18 INDUCES NK DEFICIENCY BUT DRIVES HYPERINFLAMMATION VIA CD8 T-CELL CYTOKINE OVERPRODUCTION AND SELECTIVE IMMUNODEFICIENCY This study suggested that IL18 may promote MAS through amplification of CD8 T-cell cytokine amplification and impairment of viral clearance. |