Stefan Dinescu
Stefan is a rheumatology specialist and lecturer at the University of Medicine and Pharmacy Craiova (Romania). His main research interests include rheumatoid arthritis, spondyloarthritis and musculoskeletal ultrasound. Stefan is a member of the EMEUNET Education Sub-Committee.
| Poster 1336 | Sunday, 12.11.23 09:00 RA – Treatments Poster II Author: De Jong, P (Netherlands) Title: ADALIMUMAB AND ETANERCEPT SERUM LEVELS IN RHEUMATOID ARTHRITIS PATIENTS WITH AND WITHOUT A DISEASE FLARE DURING TAPERING  Results offer a critical threshold for serum levels of TNFi which could be used during tapering of biologics to prevent flares. |
| Oral 0835 | Sunday, 12.11.23 16:00 RA – Treatments I: Novel RA Treatments & Mechanisms of Action Author: Cope, A (UK) Title: ABATACEPT IN INDIVIDUALS AT RISK OF DEVELOPING RHEUMATOID ARTHRITIS: RESULTS FROM THE ARTHRITIS PREVENTION IN THE PRE-CLINICAL PHASE OF RA WITH ABATACEPT (APIPPRA) TRIAL T cell co-stimulation modulation with abatacept in patients at risk showed reduction of RA development over two years. |
| Oral 0838 | Sunday, 12.11.23 16:00 RA – Treatments I: Novel RA Treatments & Mechanisms of Action Author: Ross, R (USA) Title: INFUSION OF ETANERCEPT INTO THE PERIPHERAL LYMPHATICS SIGNIFICANTLY REDUCES DISEASE ACTIVITY IN RHEUMATOID ARTHRITIS PATIENTS WITH INADEQUATE RESPONSE TO SUBCUTANEOUS INJECTIONS Administering TNF inhibitors in peripheral lymphatics proved efficacy in inadequate responders and may reduce dose frequency. |
| Poster 2160 | Tuesday, 14.11.23 09:00 Abstracts: RA – Treatment Poster III Author: David, P (UK) Title: POLY-REFRACTORY RHEUMATOID ARTHRITIS: ALL b/tsDMARD CLASSES EXHAUSTED – AN UNCOMMON DISEASE SUBSET WITH DISTINCT INFLAMMATORY AND NON-INFLAMMATORY PHENOTYPES Poly-refractory RA represented only 2.5% of RA cases under b/tsDMARDs and at least a third of cases did not exhibit objective signs of active inflammation on ultrasound. |
| Oral 2541 | Tuesday, 14.11.23 16:00 Abstracts: RA – Treatments III: Predictors of Response & Tapering Author: Baker, J (USA) Title: DIFFERENTIAL RESPONSES TO INITIAL TREATMENT STRATEGIES FOR RHEUMATOID ARTHRITIS AMONG THOSE WITH LOWER BODY MASS AND ADIPOSITY This study shows that both low BMI and evidence of low adiposity based on adipokine profiles are associated with a superior response to initiation of TNFi compared to the initiation of triple therapy. |
| Oral 2543 | Tuesday, 14.11.23 16:00 Abstracts: RA – Diagnosis, Manifestations, & Outcomes III: Predicting & Optimizing Outcomes Author: Kjørholt, KE (Norway) Title: CLINICAL AND RADIOGRAPHIC RESULTS OF TAPERING AND WITHDRAWING CSDMARDS VERSUS STABLE TREATMENT IN PATIENTS WITH RHEUMATOID ARTHRITIS IN REMISSION: 3-YEAR RESULTS FROM A RANDOMIZED CONTROLLED TRIAL Data shows that 38% of patients who withdrew csDMARDs after 1-year tapering achieved long-term drug-free remission, which indicates that this could be an option for some RA patients in sustained remission. |