EULAR 2024: Do Not Miss – Basic and Translational Research I

Bohdana Doskaliuk
Bohdana D. is a PhD fellow at the Ivano-Frankivsk National Medical University, Ukraine. Her main research interests include the pathogenesis of SSc-ILD and animal models of rheumatic diseases. Bohdana D. is a member of the EMEUNET Country Liaison Sub-Committee.

Oral 0038 | Wednesday 12.06.2024 16.50
Basic Abstract Session (RA pathogenesis and novel therapeutic targets)
Author:   Miyagawa, I (Japan)
Title: Unravelling The Gut-joint Connection In Rheumatoid Arthritis: The Role Of Intestinal Acetylated Proteins

This abstract presents that acetylated proteins in the gut may trigger early autoantibody production in RA, exacerbating the disease by cross-reacting with joint tissue antigens.
Poster 0021 | Wednesday 12.06.2024 14.00
Poster Tour 6 (Osteoarthritis & Joint Biology – Basic Science)
Author: Zhou, X (Germany)
Title: Metabolic Targeting By Sodium Pyruvate Prevent Fibroblast-to-myofibroblast Transition And Fibrotic Remodeling

This abstract demonstrates that sodium pyruvate supplementation improves
mitochondrial function and metabolic balance, reducing fibrosis in systemic
sclerosis by inhibiting fibroblast activation and collagen production.
Oral 0189 | Thursday, 13.06.24 11.30
Basic Abstract Session (Immune cell activation across inflammatory diseases)
Author: Martinez-Canales, R (Mexico)
Title: Molecular Mechanisms And Immune Cell Patterns In Peripheral Blood Associated To Coronary Atherosclerosis In Patients With Systemic Lupus

This abstract describes the identification of specific genes and immune cell patterns associated with coronary artery atherosclerosis in patients with SLE.
Oral 0204 | Thursday, 13.06.24 11.40
Basic Abstract Session (Pathophysiology in systemic sclerosis disease)
Author: Papadimitriou, M (Australia)
Title: Effect Of Ft011 Treatment On Revised Criss-25 And Gene Expression In Skin Biopsies From Patients With Diffuse Cutaneous Systemic Sclerosis

This abstract presents that FT011 shows promising efficacy in treating diffuse
SSc by improving clinical outcomes and reducing fibrotic gene expression after
12 weeks of treatment.
Poster 0303 | Friday, 14.06.2024 12.00
Poster Tour 4 (Molecular insights into PsA and SpA)
Author: Mauro, D (Italy)
Title: Crossing The Barriers: Dysbiosis And Subclinical Uterine Inflammation In The Pathogenesis Of Axspa In Females. Another Break In The Wall?

This abstract reveals that uterine barrier may play a role in the pathogenesis of
SpA in female patients.
Oral 0388 | Saturday, 15.06.2024 10.15
Poster Tour 3 (Pathophysiological concepts in Lupus and lupus nephritis)
Author: Guthridge, JM (USA)
Title: Integrated Soluble Proteomics And Autoreactomics: Predicting Renal Involvement In Systemic Lupus Erythematosus

This abstract highlights the integration of machine-learning models to prediction of renal involvement in SLE.

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