ACR Convergence 2024: Do Not Miss – Vasculitis and other connective tissue diseases

Rositsa Dacheva

Rositsa Dacheva is a rheumatologist from Sofia, Bulgaria. Rositsa is a member of EMEUNET Newsletter Sub-Committee and a Country Liaison for Bulgaria

Poster 0685 | Saturday, November 16, 2024 10:30
Systemic Sclerosis & Related Disorders – Clinical Poster I
Presenting author: Siero Santos, C (Spain)
Title: KL-6 and IL-18 Biomarkers in Systemic Sclerosis-associated Interstitial Lung Disease: Enhancing Prognostic Insights into Early Detection, Progressive, Lung Volume Changes, and Mortality Risk

This prospective study aims to assess  serum biomarker KL-6 and IL-18 as lung-specific predictors of ILD progression in SSc and their discriminative capabilities in differentiating between various grades of fibrosis identified through semiquantitative CT imaging in systemic-sclerosis-associated interstitial lung disease.
Poster 0762 | Saturday, November 16, 2024 10:30
Vasculitis-Non-ANCA-Associated & Related Disorders Poster I, Poster Session A
Presenting author: M Amar Muñoz, H (Spain)
Title: Different Giant Cell Arteritis Phenotypes May Present Distinct Types of Ischemic Complications

This retrospective study’s objective is to determine whether the subtype of vascular ultrasound presentation is associated with different types of ischemic complications in giant cell arteritis (GCA).
Poster 1418 | Sunday, November 17, 2024 10:30
Sjögren’s Syndrome – Basic & Clinical Science Poster I
Presenting author: Aue, A (Germany)
Title: Soluble Immune Checkpoint Molecules as Biomarkers for Extraglandular Sjögren’s Disease

The abstract reveals the role of soluble checkpoint molecules as potential biomarkers in primary Sjögren syndrome (pSS). The study demonstrates that patients with both primary and secondary SS had significantly higher circulating levels of sPD-L1 compared to healthy controls, while s4-1BB were significantly higher only in secondary SS.
Poster L06 | Monday, November 18, 2024 10:30
(L01-L14) Late Breaking Posters, Poster Session C, 2024, Myositis
Presenting author: Kirou, R (USA)
Title: Distinct Cytokine and Cytokine Receptor Expression Patterns Characterize Different Subtypes of Inflammatory Myopathies

The study performs RNA sequencing analysis to identify cytokines, cytokine receptors, and checkpoint genes specific for each different myositis subtype. The analysis included 669 patients. The study demonstrates the expression of distinct inflammatory mediators in different myositis subtypes, highlighting potential insights into the pathogenesis of the disease.
Poster 1962 | Monday, November 18, 2024 10:30
Imaging of Rheumatic Diseases Poster II
Presenting author: Eshak, N (USA)
Title: Utility of 18 FDG-PET/CT Scans in the Diagnosis of Polyarteritis Nodosa and Other Medium Vessel Vasculitis

The study demonstrates the utility of 18 FDG-PET/CT Scans in the diagnosis of Medium Vessel Vasculitis, suggesting the role of imaging procedures in improving diagnostic accuracy, addressing a critical unmet need in the field.
Poster 2004 | Monday, November 18, 2024 10:30
Clinical Poster Tours: Clinical aspects of small vessel vasculitis – Part 1
Presenting author: Alfredo Gomez-Puerta, J (Spain)
Title: Rheumatic Complications Post-CAR-T Cell Therapy. Experience of a Single Center

The study aims to assess rheumatological complications post-CAR-T cell therapy in 310 patients with hematological malignancies treated between 2020 and 2024.
Poster 1857 | Monday, November 14, 2024 01:00
Muscle Biology, Myositis and Myopathies Poster II
Presenting author: Hannah, J (United Kingdom)
Title: Increasing Proportion of MDA-5 Associated Conditions in a Tertiary Myositis Centre Following Onset of the Covid-19 Pandemic

This is a retrospective analysis assessing whether the incidence of anti-MDA5 DM increased following the onset of the Covid-19 pandemic. 2,627 patients were included in the analysis, revealing  increasing proportion of MDA-5 associated conditions following onset of the Covid-19 pandemic.

Leave a Reply