ACR Convergence 2026: Do Not Miss – Spondyloarthritis (non-therapeutic)

Agata Schramm-Luc

Agata is an internist and rheumatologist. She is a lecturer (research/teaching) in the Department of Internal and Rural Medicine of the Jagiellonian University in Krakow, Poland, where she earned a PhD in medicine for research entitled “T cell proinflammatory cytokine production and clinical manifestations of inflammatory diseases.”

In her work she combines practice in the Rheumatology Outpatient Clinics with research in the Translational Medicine Laboratory. Her main scientific interest is the role of the immune system in hypertension in rheumatoid arthritis and spondyloarthritis.

Agata is an active member of the Young Rheumatologists’ Sub-Committee of Polish Society of Rheumatology, member of the Polish Society of Internal Medicine and a member of the EMEUNET Peer-Mentoring Sub-Committee.

ORAL 0883 | Sunday, 08.11.2026 09:45
Abstract Session: Spondyloarthritis Including Psoriatic Arthritis – Diagnosis, Manifestations, & Outcomes I
Presenting author: Ayyanna H. (India)
Title: Development and Validation of the Reactive Arthritis and Peripheral Spondyloarthritis Activity Score (RAPSAS)

This study presents a disease activity score for reactive arthritis and peripheral spondyloarthritis developed from existing literature and expert consensus and validated in a prospective cohort of patients. The final RAPSAS, composed of 7 items (number of swollen joints, number of tender joints, duration of morning stiffness, NRS of inflammatory backache, NRS of Patient Global, NRS of Physician Global, and CRP) demonstrated strong content validity, known group validity, internal consistency, test-retest reliability, and sensitivity to change.
POSTER 0391 | Sunday, 08.11.2026 10:30
Poster Session: Spondyloarthritis Including Psoriatic Arthritis – Diagnosis, Manifestations, & Outcomes Poster A
Presenting author: Eder L. (Canada)
Title: More than Pain: Differences in Symptom Profile and Their Relation With Psoriatic Arthritis Activity in Male and Female Patients Enrolled in a Global Cohort Study

This study, characterizing differences in symptom patterns in male and female patients with active psoriatic arthritis prior to treatment initiation, demonstrated that despite similar disease activity, female patients presented with greater nociplastic pain, cognitive, somatic and mood symptoms, fatigue, sleep disturbance, psychological symptoms, physical dysfunction, and lower health-related quality of life potentially contributing to treatment outcomes.
POSTER 0377 | Sunday, 08.11.2026 10:30
Poster Session: Spondyloarthritis Including Psoriatic Arthritis – Diagnosis, Manifestations, & Outcomes Poster A
Presenting author: DeMits, S (Belgium)
Title: Anti-14-3-3eta Autoantibodies Support Differential Diagnosis of Axial Spondyloarthritis (axSpA) from Mechanical and Non-AxSpA Back Pain

This study, evaluating the ability of anti-14-3-3eta autoantibodies to differentiate axSpA from other conditions with similar clinical presentations, demonstrated that these antibodies, combined with age and sex, yield an AUC of 0.88 (95% CI: 0.83-0.93) with 90% specificity, 67% sensitivity, and a diagnostic odds ratio of 18.4 for distinguishing axSpA from mechanical back pain. Anti-14-3-3eta autoantibodies also showed the ability to differentiate axSpA from the broader non‑axSpA cohort, indicating their utility as an adjunctive diagnostic tool.
POSTER 1670 | Monday, 09.11.2026 10:30
Poster Session: Infection-Related Rheumatic Disease Poster B
Presenting author: Miller J. (USA)
Title:
Spondyloarthritis may be an Underrecognized Cause of Persistent Musculoskeletal Pain following Lyme Disease

This prospective, observational study characterizes the clinical spectrum of post-Lyme autoimmune arthritis and estimates the frequency of inflammatory arthritis in patients with post-treatment Lyme disease with prominent musculoskeletal pain. In this group, 33% (7 of 21) of patients were diagnosed with spondyloarthritis, often with prominent enthesitis. This study suggests that the prevalence of SpA after Lyme disease may be greater than previously estimated.
ORAL 1825 | Monday, 09.11.2026 11:15
Plenary Session: Plenary II
Presenting author: Maksymowych W. (Canada)
Title: Defining an MRI Indicative of Axial Spondyloarthritis in the Sacroiliac Joints of Patients with Axial Spondyloarthritis: A Data-Driven and Consensus-based Framework of Recommendations by the Spondyloarthritis Research and Treatment Network and the Society of Skeletal Radiology

This study proposes guidance for a definition of a positive MRI across the full spectrum of axial spondyloarthritis based on systematic literature review, analysis of 1050 cases from three cohorts, and consensus voting. Eight overarching principles and 10 recommendations were formed alongside a new quantitative component for a definition of a positive MRI based on BME≥3 consecutive slices OR any two of the following 3 features (BME, Erosion, Fat lesion), each lesion being present in ≥3 SIJ quadrants OR ankylosis in ≥3 SIJ halves. The proposed definition achieved high sensitivity and specificity across the three cohorts.
ORAL 2877 | Tuesday, 10.11.2026 13:30
Abstract Session: Spondyloarthritis Including Psoriatic Arthritis – Diagnosis, Manifestations, & Outcomes III
Presenting author: Saad C. (Brazil)
Title: Who Gets Left Behind? Patients Classified by ASAS 2009 but Excluded by ASAS-SPARTAN 2025 in a Real-World SpA Cohort

This study, analyzing agreement between ASAS-SPARTAN 2025 criteria and ASAS 2009 criteria in SpA cohort and characterizing patients previously classified, but excluded by the 2025 criteria, demonstrated very high agreement between criteria sets and similar discriminative performance, while the 2025 criteria showed higher operational specificity in patients with peripheral SpA. The main discordance was in imaging: sacroiliitis was present in only 39.2% of patients fulfilling 2009 but not 2025 criteria and in 99.6% of concordant patients. Additionally, inflammatory back pain, elevated CRP, heel enthesitis, and HLA-B27 positivity were independently associated with lower odds of discordance, while psoriasis and older age at symptom onset increased the odds.

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