Basic and Translational Research II

Morten Aagaard Nielsen

Morten Aagaard Nielsen, MD, Ph.D., Department of Rheumatology, Aarhus University Hospital, Denmark. His work primarily focuses on investigating the role of inflammatory fibroblasts, sucker-binding proteins and immune checkpoint receptors in immune mediated diseases. Morten is a member of the VIS&GA Subgroup.

Type, n°Date, timeSessionAuthorTitle
Oral 0094Wednesday, 31.05.2023 19:35-19:45Fibroblast activation in rheumatic diseases Reis Nisa,
PI (UK)
SPATIAL POSITIONING AND MATRIX PROGRAMS OF SYNOVIAL FIBROBLASTS UNDERPIN IMMUNE CELL ORGANISATION AND SYNOVIAL TISSUE PATHOTYPE
A functional zonation of the inflamed synovium using both spatial transcriptomics and multiplex imaging.
Oral 0015Wednesday, 31.05.2023 16:45-16:55Adaptive immunity (T cells and B cells) in rheumatic diseasesSingaraju,
A (USA)
CD38HI CYTOTOXIC CD8 T CELLS ARE EXPANDED FOLLOWING CHECKPOINT BLOCKADE AND CHARACTERIZE THE T CELL INFILTRATE IN CHECKPOINT INHIBITOR-ASSOCIATED ARTHRITIS
Investigation of the transcriptomic and clonotypic features of infiltrating T cells in joints after ICI-induced inflammatory arthritis.
Oral 0121Thursday, 01.06.2023 10:45-10:55Predictors of outcome in early rheumatoid arthritisFiler,
A(UK)
SYNOVIAL CELLULAR NICHES ARE DETERMINANTS OF ARTHRITIS PERSISTENCE VERSUS RESOLUTION IN EARLY UNTREATED ARTHRITIS
Single cell RNA sequencing from synovial tissue biopsies describing different key cellular niches between resolution and persistence of active arthritis in RA and PsA.
Poster 0040Thursday, 01.06.2023 12:05-12:10Disease mechanisms in spondylarthritisRauber,
S (Germany)
SILENCING OF JOINT FIBROBLAST TO PROTECT FROM JOINT DAMAGE
In vitro and in vivo therapeutic reprogramming of inflammatory FLS – as a potential treatment approach in arthritides.
Oral 0186Thursday, 01.06.2023 14:35-14:45Single-cell omics in Rheumatic diseases​Horisberger,
A (USA)
DISTINCT PERIPHERAL IMMUNOPHENOTYPING UNDERLINES HISTOPATHOLOGICAL FEATURES IN PATIENTS WITH LUPUS NEPHRITIS IN A LARGE MULTI-CENTER COHORT
A characterization of circulating immune cell phenotypes predicting lupus nephritis histology – nominating potential non-invasive biomarkers.
Oral 0106Thursday, 01.06.2023 10:55-11:05Innate Immunity in Pathogenesis of RMDsRaimondo,
MG(Germany)
SYNOVIAL IMPRINTING OF SKIN-DERIVED IMMUNE CELLS INITIATES SPREADING OF INFLAMMATION FROM SKIN TO JOINT IN PSORIATIC ARTHRITIS
In vivo investigation of the spreading of psoriatic inflammation from the skin to the joints – addressing thee role in PsA pathogenesis.
Oral 0203Friday, 02.06.2023 10:45-10:55Understanding Treatment response and novel treatment approaches in RAKubo,
S (Japan)
IMMUNOPHENOTYPING OF RHEUMATOID ARTHRITIS STRATIFIES FIVE GROUPS THAT HAVE DIFFERENT RESPONSES TO MOLECULAR TARGETED THERAPIES
Immune phenotyping of peripheral blood, to stratified RA patients to different molecular targeted therapies.

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